GABASIGN 400 CAP is a high-quality oral medication containing Gabapentin 400 mg, used to manage chronic nerve pain, epilepsy, and postherpetic neuralgia. Gabapentin is a structural analogue of the neurotransmitter GABA but exerts its effects by binding to voltage-gated calcium channels in the CNS, helping regulate nerve signals that cause pain or seizures.

Manufactured by BluepillExpress, a WHO-GMP and ISO-certified Indian pharmaceutical company, GABASIGN 400 is developed using advanced formulations, state-of-the-art manufacturing technologies, and the highest-quality active pharmaceutical ingredients (APIs). It is widely accepted and trusted across global markets due to its robust therapeutic performance, affordability, and regulatory conformity.

Therapeutic Indications

Neuropathic pain caused by diabetes, spinal injury, or viral infections

Postherpetic neuralgia (pain after shingles)

Adjunct therapy in partial seizures

Fibromyalgia and restless leg syndrome (off-label)

Other nerve-related pain conditions

Mechanism of Action

Gabapentin binds to the alpha-2-delta subunit of presynaptic voltage-gated calcium channels, reducing calcium influx and inhibiting the release of excitatory neurotransmitters. This mechanism stabilizes abnormal electrical activity in the brain and spinal cord, relieving pain and controlling seizures.

Dosage & Administration

Starting dose: Typically initiated at 300 mg and increased gradually based on therapeutic response

Maintenance dose: 900–1800 mg/day divided in 2–3 doses

GABASIGN 400 is often used when titration has already reached intermediate-to-high levels

Dosage should be tailored by a medical professional depending on the patient’s condition and tolerance.