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ES-PROZOLE DSR TAB is a combination gastro-protective formulation containing Esomeprazole 40 mg and Domperidone 30 mg, engineered in dual-release technology to treat acid reflux, GERD, and functional dyspepsia. Esomeprazole suppresses gastric acid production while Domperidone acts as a prokinetic, enhancing gastrointestinal motility and controlling nausea. Manufactured by BluepillExpress, this DSR (Dual Sustained Release) tablet ensures both rapid and extended symptom relief. Ideal for third-party pharma manufacturing, hospital supply, and international distribution, ES-PROZOLE DSR is widely accepted in gastroenterology practices.
This product is manufactured under the Dr Precision label, ensuring GMP-compliant quality and precision formulation standards.
ES-PROZOLE DSR TAB, manufactured by BluepillExpress, is a scientifically advanced, dual-layered gastroenterological tablet combining the powerful proton pump inhibition of Esomeprazole with the prokinetic and antiemetic action of Domperidone. It is specially designed to offer long-lasting relief from acid-related disorders such as gastroesophageal reflux disease (GERD), non-ulcer dyspepsia, gastritis, and nausea-vomiting associated with delayed gastric emptying.
This formulation combines Esomeprazole 40 mg, delivered as enteric-coated granules, ensuring it bypasses the stomach for targeted intestinal absorption, and Domperidone 30 mg, provided in a sustained-release format to maintain therapeutic levels over an extended period. This dual-release action ensures both immediate symptom control and prolonged acid suppression for a full 24-hour coverage.
Domperidone enhances gastrointestinal motility by acting on dopamine D2 receptors in the GI tract, promoting faster gastric emptying and reducing bloating, nausea, and abdominal discomfort. The synergy between Esomeprazole and Domperidone makes ES-PROZOLE DSR a frontline therapy in acid reflux management and gastric motility disorders.
With WHO-GMP certified production standards, ES-PROZOLE DSR TAB meets the stringent quality, safety, and efficacy criteria demanded by global healthcare markets. It is formulated using advanced pelletization and delayed-release coating technology, ensuring bioequivalence, patient compliance, and consistent therapeutic outcomes.
✅ Indications / Therapeutic Uses
Gastroesophageal Reflux Disease (GERD)
Non-ulcer Dyspepsia
Acid Peptic Disorders
Chronic Gastritis
Functional Bloating and Nausea
Reflux Esophagitis
Delayed Gastric Emptying
Vomiting associated with gastric stasis
✅ Mechanism of Action
Esomeprazole irreversibly inhibits the H+/K+ ATPase enzyme system of gastric parietal cells, which is the final pathway for acid secretion, thereby reducing gastric acidity significantly and for a prolonged period.
Domperidone works by antagonizing dopamine D2 receptors in the GI tract and the chemoreceptor trigger zone, promoting gastric emptying and improving lower esophageal sphincter tone while minimizing symptoms like nausea and fullness.
✅ Dosage & Administration
Typical dosage: One tablet/capsule per day
Administration: Take orally on an empty stomach, preferably 30 minutes before breakfast
Duration: Course typically lasts 4 to 8 weeks, depending on indication
Always follow physician's guidance on duration and dosage
