EMPARA 1000 TAB is a high-strength formulation of Metformin Hydrochloride, a well-established and widely used oral biguanide-class antidiabetic agent. It is primarily prescribed for the management of Type 2 Diabetes Mellitus, especially in overweight patients when dietary management and lifestyle changes alone are insufficient. The formulation aids in achieving glycemic control without causing weight gain or hypoglycemia when used as monotherapy.

Metformin works by decreasing hepatic glucose production, enhancing peripheral glucose uptake, and improving insulin sensitivity. Unlike sulfonylureas, Metformin does not stimulate insulin secretion, making it safer with a lower risk of hypoglycemia. EMPARA 1000 TAB is suitable as a monotherapy or in combination with other antidiabetic medications such as sulfonylureas, DPP-4 inhibitors, SGLT2 inhibitors, or insulin.

Manufactured under WHO-GMP and ISO-certified facilities by BluepillExpress, EMPARA 1000 TAB is available for bulk export, contract manufacturing, and custom branding in compliance with international standards. The formulation is ideal for pharmaceutical companies looking to register and distribute a reliable high-dose Metformin product globally.

✅ Therapeutic Indications

Type 2 Diabetes Mellitus (T2DM)

Prediabetes (off-label use)

Polycystic Ovary Syndrome (PCOS – off-label)

Insulin resistance management

Adjunct therapy in obesity-related glucose disorders

✅ Mechanism of Action

Metformin reduces hepatic glucose output, increases insulin sensitivity in muscle cells, and enhances peripheral glucose uptake. It also decreases intestinal absorption of glucose, resulting in:

Lower fasting and postprandial blood sugar levels

Improved glycemic control

No associated risk of hypoglycemia in monotherapy

Favorable impact on lipid profile and weight management

✅ Pharmacological Benefits

First-line therapy for newly diagnosed Type 2 diabetes

Helps in weight neutrality or mild weight loss

Low risk of hypoglycemia

Proven cardiovascular safety profile

Can delay the progression from prediabetes to diabetes

Safe and effective long-term use backed by global clinical studies

✅ Dosage & Administration

Typical Dose: 1000 mg once or twice daily (depending on clinical condition)

Maximum Daily Dose: 2000–2550 mg/day (in divided doses)

Route: Oral

Administration: With meals to reduce gastrointestinal side effects

Duration: Long-term maintenance as advised by the healthcare provider