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CLOZOLE-V6 Tablet is a powerful intravaginal antifungal treatment containing Clotrimazole 100 mg, used to treat vulvovaginal candidiasis and other fungal infections affecting the vaginal mucosa. Each tablet is designed for local application inside the vagina, delivering high concentrations of the active antifungal agent directly to the site of infection. Manufactured by BluepillExpress under WHO-GMP standards, CLOZOLE-V6 provides a safe, effective, and well-tolerated option for restoring vaginal health over a standard 6-day treatment course.
This product is manufactured under the Dr Precision label, ensuring GMP-compliant quality and precision formulation standards.
CLOZOLE-V6 Tablet is a vaginal antifungal formulation used to treat infections caused by Candida species, primarily Candida albicans, which is the most common pathogen responsible for vulvovaginal candidiasis (VVC). The formulation contains Clotrimazole, an imidazole-class antifungal agent, known for its broad-spectrum fungistatic and fungicidal activity. This product is intended for intravaginal use only and is formulated as a vaginal tablet that dissolves at body temperature for localized, sustained antifungal action.
Mechanism of Action:
Clotrimazole exerts its antifungal activity by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes. This disruption in membrane integrity causes leakage of cellular contents, leading to fungal cell death. The localized vaginal application allows for high drug concentrations directly at the site of infection, resulting in rapid symptom relief and microbial eradication.
Clinical Indications:
CLOZOLE-V6 is primarily indicated for:
Vulvovaginal candidiasis (VVC)
Recurrent yeast infections
Symptomatic relief of itching, burning, and discharge associated with fungal vaginitis
Adjunctive therapy in mixed vaginal infections (when fungal component is confirmed)
Advantages of CLOZOLE-V6:
Delivers targeted therapy to the infection site
Minimizes systemic absorption and adverse effects
Convenient once-daily application over six days
Does not interfere with the natural pH of the vaginal environment
Rapid resolution of clinical symptoms like itching, redness, and discharge
Proven efficacy in single-pathogen and mixed-pathogen infections
Formulation and Composition:
Each vaginal tablet contains:
Clotrimazole IP 100 mg
Excipients: Lactose, microcrystalline cellulose, starch, and other pharmaceutical-grade tablet bases designed to facilitate rapid disintegration and mucosal adherence within the vaginal cavity.
Dosage and Administration:
One vaginal tablet should be inserted deep into the vagina once daily, preferably at bedtime.
The usual course is for 6 consecutive days (hence V6).
Patients should be advised to complete the full course of treatment even if symptoms resolve earlier.
